La Paz to Santiago

Set off on an unforgettable adventure through the soaring Andes, meeting friendly locals and discovering the rich culture and breathtaking scenery of this remarkable region. Starting in vibrant La Paz, this incredible journey takes in some of Bolivia's most spectacular scenery including the mesmerising salt flats of Salar de Uyuni and fiery-red Laguna Colorada before crossing into Argentina. Indulge in some world-renowned wines in Cafayate, then explore the Pampas on horseback and savour the succulent flavours of a traditional barbecue while staying on a working cattle ranch. Soak up the relaxed atmosphere of Mendoza before finishing the adventure in sensational Santiago. This amazing journey is the perfect way to experience the best of this magnificent region.


Days 1-2 La Paz

Start the journey in one of South America's most fascinating cities. Browse the city's many bustling markets or visit the stimulating Coca Museum to discover the history and usage of this plant.

Days 3-4 Potosi

Soak up the barren yet impressive Andean landscapes en route to this colonial mining town. An optional tour of a working mine provides a fascinating and somewhat hair-raising insight into life in the region.

Days 5-6 Salar de Uyuni

Gaze in awe at the seemingly endless expanse of Bolivia's largest salt flats before admiring the remarkable red waters of Laguna Colorada.

Days 7-8 Bolivian Altiplano/San Pedro de Atacama

Journey towards the Argentine border, camping among spectacular scenery.

Days 9-11 Salta

Delight in the laidback atmosphere of this elegant colonial city. Relax in the main plaza, discover the pumping nightlife or head out of town to Quebrada de Humahuaca, a narrow valley flanked by spectacularly colourful mountains and giant cacti.

Day 12 Cafayate

Learn about local wine production on a guided vineyard tour, perhaps taking the opportunity to indulge in some renowned blends.

Days 13-16 Estancia stay

Experience Argentine hospitality while staying on a working cattle ranch. Perhaps explore the Pampas on horseback before savouring the mouth-watering aromas and succulent flavours of a traditional barbecue.

Days 17-19 Mendoza

Traverse the high passes of the Andes en route to this delightful provincial area. Relax in the shade of the trees that line the city's wide avenues, visit local art galleries or chill out with a glass of wine.

Days 20-21 Santiago

Celebrate the end of an unforgettable adventure in Chile's cosmopolitan capital.

View more about La Paz to Santiago Trip
Need More Help?
1-866-549-7614 or Send Email

Related Travel Stories

The Bewildering Beauty of Argentina

You'll be amazed and awed at the breathtaking beauty of the Patagonia and impressed with the cosmopolitan and European-like streets of Buenos Aires. With stunning natural beauty, delicious, rich cuisine Argentina is sure not to disappoint any adventurous traveler. ...

The Secret of Iguazu

In the middle of beautiful, but touristy, Iguazu Falls National Park, there exists a secret paradise that backpackers can have all to themselves....

Like This Trip? Please Share